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ATCC
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Thermo Fisher
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Thermo Fisher
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ACROBiosystems
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ATCC
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ATCC
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Microbix Inc
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LGC Promochem
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Qiagen
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Image Search Results
Journal: Analytical Chemistry
Article Title: SCORe: SARS-CoV-2 Omicron Variant RBD-Binding DNA Aptamer for Multiplexed Rapid Detection and Pseudovirus Neutralization
doi: 10.1021/acs.analchem.2c01993
Figure Lengend Snippet: Schematic of the SELEX process. A single-stranded DNA (ssDNA) aptamer library is subjected to SARS-CoV-2 Omicron (BA.1) S1 protein for seven rounds of positive selection with increasing stringency and SARS-CoV-2 Omicron (BA.1) NTD negative selection in rounds 6 and 7 only. Binding of aptamer round pool is evaluated by protein-binding assay, and aptamer round pools with positive binding are sequenced and analyzed.
Article Snippet: BA.1 SARS-CoV-2 S protein S1 domain (ACROBiosystems S1N-C52Ha), BA.1 SARS-CoV-2 S protein trimer (ACROBiosystems SPN-C52Hz), BA.1 SARS-CoV-2 S protein NTD (ACROBiosystems SPD-C522df), BA.1 SARS-CoV-2 S protein RBD (ACROBiosystems SPD-C522e), BA.2 SARS-CoV-2 S protein RBD (ACROBiosystems SPD-C522g),
Techniques: Selection, Binding Assay, Protein Binding
Journal: Analytical Chemistry
Article Title: SCORe: SARS-CoV-2 Omicron Variant RBD-Binding DNA Aptamer for Multiplexed Rapid Detection and Pseudovirus Neutralization
doi: 10.1021/acs.analchem.2c01993
Figure Lengend Snippet: (A) LFA schematic. (B) Detection and differentiation between Omicron (BA.1) and wild-type SARS-CoV-2 S protein. “None” and “0 pM” indicate negative controls, which were treated identically as other samples except with no S protein added. Bars indicate mean. Parentheses indicate S.D. Statistical significance determined by one-way ANOVA with Dunnett correction; ** indicates p < 0.01, **** indicates p < 0.0001 when compared to no protein; n = 3 per experimental group. Representative images are shown.
Article Snippet: BA.1 SARS-CoV-2 S protein S1 domain (ACROBiosystems S1N-C52Ha), BA.1 SARS-CoV-2 S protein trimer (ACROBiosystems SPN-C52Hz), BA.1 SARS-CoV-2 S protein NTD (ACROBiosystems SPD-C522df), BA.1 SARS-CoV-2 S protein RBD (ACROBiosystems SPD-C522e), BA.2 SARS-CoV-2 S protein RBD (ACROBiosystems SPD-C522g),
Techniques: